The Detweiler Lab

MCD Biology - Creative early stage antibiotic discovery

Nagy TA, Crooks AL, Quintana JLJ, Detweiler CS. 2020. Clofazimine Reduces Survival of Salmonella enterica in Macrophages and Mice. ACS Infectious Diseases.

Detweiler CS. 2020. Infection-based chemical screens uncover host-pathogen interactions. Current Opinion in Microbiology. Review.

Reens AL, Nagy TA, Detweiler CS. 2019. Salmonella enterica Requires Lipid Metabolism Genes to Replicate in Pro-inflammatory Macrophages and Mice. Infection and Immunity. Featured Spotlight Article.

Nagy TA, Quintana JLJ, Reens AL, Crooks AL, Detweiler CS. 2019. Autophagy Induction by a Small Molecule Inhibits Salmonella Survival in Macrophages and Mice. Antimicrobial Agents Chemotherapy.

Reens AL, Crooks AL, Su C-C, Nagy TA, Reens DL, Podoll JD, Edwards ME, Yu EW, Detweiler CS. 2018. A Cell-Based Infection Assay Identifies Efflux Pump Modulators That Reduce Bacterial Intracellular Load. PLOS Pathogens.

Courtney CM, Goodman SM, McDaniel JA, Madinger NE, Chatterjee A, Nagpal P. 2016. Photoexcited quantum dots for killing multidrug-resistant bacteria. Nature Materials.

Bauler TJ, Starr T, Nagy TA, Sridhar S, Scott D, Winkler CW, Steele-Mortimer O. Detweiler CS, Peterson KE. Salmonella Meningitis Associated with Monocyte Infiltration in Mice. 2016 The American Journal of Pathology.

McQuate SE, Young AM, Silva-Herzog E, Bunker E, Hernandez M, de Chaumont F, Liu X, Detweiler CS, Palmer AE. 2016. Long-Term Live Cell Imaging Reveals New Roles For Salmonella Effector Proteins SseG and SteA. Cellular Microbiology.

Silva-Herzog E, McDonald EM, Crooks AL, Detweiler CS. 2015. Physiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses. PLOS ONE.

McDonald EM, Pilonieta MC, Nick HJ, Detweiler CS. 2015. Bacterial Stimulation of Toll-Like Receptor 4 Drives Macrophages to Hemophagocytose. Infection and Immunity.

Brown DE, Nick HJ, McCoy MW, Moreland SM, Stepanek AM, Benik R, O'Connell KE, Pilonieta MC, Nagy TA, Detweiler CS. 2015 Increased ferroportin-1 expression and rapid splenic iron loss occur with anemia caused by Salmonella infection in mice. Infection and Immunity.

Teske SS, Detweiler CS. The biomechanisms of metal and metal-oxide nanoparticles’ interactions with cells. 2015. Int J Environ Res Public Health.

Pilonieta MC, Moreland SM, English CN, Detweiler CS. 2014. Salmonella enterica infection stimulates macrophages to hemophagocytose. mBio.

Nagy TA, Moreland SM, Detweiler CS. 2014. Salmonella acquires ferrous iron from haemophagocytic macrophages. Molecular Microbiology.