MCDB News:

Kent Riemondy

August 18, 2015

DNA mutations occur and accumulate during an individual's lifetime. Often these changes are harmless. But some mutations‐called driver mutations‐can trigger the formation of tumors. This is often because these mutations allow the cells to grow faster than normal cells. Mutations in genes in the Ras gene family are among the most common driver mutations found in human cancers. These common mutations lead to the uncontrolled activation of genes that are normally tightly controlled, which in turn allows the cells to divide more and live for longer: these are two key features of cancer cells.
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